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Solutions for ones receptive to the superior virtues of brain support.


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Good Health Demands the Benefits of Premium Brain Support™

"GOOD HEALTH assigns a premium value to brain support. True brain power comes from knowledge in action. MEND Solutions™ relies on Nature's purest ingredients. They are the ways and means for a healthy brain and rich life. When life presents opportunities and challenges use these tools to increase your chances of success."

Carl R. Hansen, Jr., M.D.
Founder and President


MEND Solutions™ Premium Brain Support™ was designed to meet the special nutritional requirements associated with depression through the use of coenzyme and stabilized vitamin technology.

  • Research shows that homocysteine, a toxic amino acid, is associated with depression.
  • About one-third of all depressed patients have low levels of Vitamin B-12 or folic acid.
  • To improve mood, support memory, and reduce homocysteine levels, people historically have paid $300 to $400 a month for a combination of supplements comparable to MEND Solutions™ Premium Brain Support™.

Because a single product didn't exist that delivered these benefits at a reasonable price MEND Solutions™ Premium Brain Support™ is unique as an affordable, premium quality supplement supporting brain health.

It is now clear that MEND Solutions™ Premium Brain Support™ is essential to anyone seeking the GOOD HEALTH benefits of state-of-the-art vitamin supplementation.

B-Vitamin deficiencies are associated with dementia. For example, about 16% of dementia patients have Vitamin B-12 deficiency. Not surprisingly, a Harvard study linked Alzheimer's disease to elevated homocysteine blood levels.

Dementia and heart disease are also more common in depressed people.

The body rids itself of homocysteine build-up with the aid of essential nutrients:

  • Coenzyme Vitamin B-12 (methylcobalamin) and folate (5-methyltetrahydrofolate) help convert homocysteine into methionine.
  • Coenzyme Vitamin B-6 (pyridoxal-5-phosphate) helps convert homocysteine into cysteine.
  • Trimethylglycine also works to convert homocysteine back into methionine.

World-wide, one in five pregnant women has folic acid deficiency. Studies show folic acid supplementation reduces the risk of spina bifida and other neural tube defects. As a result, folic acid has been added to foods.

Homocysteine levels have fallen dramatically with the introduction of folic acid fortification of food. Early indications are that folic acid fortification has also reduced the risks of Down's syndrome and childhood leukemia.

Folic acid fortification, however, carries some risks for individuals with Vitamin B-12 deficiency. Folic acid supplementation can mask Vitamin B-12 deficiency and can hasten the neurological damage associated with Vitamin B-12 deficiency.

Consequently, Vitamin B-12 supplementation is equally important. Everyone over age 50 should use a Vitamin B-12 supplement. Dietary sources often fail to meet their Vitamin B-12 requirements. Total plasma homocysteine also increase with Vitamin B-12 deficiency and age.

Historically, cyanocobalamin injections have been used to treat pernicious anemia. Pernicious anemia is an autoimmune disorder that leads to a reduction or failure in the absorption of Vitamin B-12. It is now known that oral administration of higher doses (1000 micrograms) are as effective as the injections.

Hygiene, digestive health, and infections play major roles in Vitamin B-12 absorption. In Guatemala, one in three children has deficient or marginal Vitamin B-12 levels. Most of these children have problems with chronic infections and bacterial overgrowth, which interfere with Vitamin B-12 absorption.

Vegetarians, and people who eat very little meat, run the risk of developing Vitamin B-12 deficiency. Many vegetarians also have elevated homocysteine levels. Vitamin supplementation is essential for anyone in this category.

A growing body of scientific research demonstrates the value of nutritional supplementation for sustaining good health and avoiding vitamin deficiencies.

Two key ingredients of MEND Solutions™ Premium Brain Support™ are coenzyme Vitamin B-12 (methylcobalamin) and stabilized folate (calcium folinate).

Methylcobalamin is the most common coenzyme form of Vitamin B-12 found in the blood. The other coenzyme form of Vitamin B-12 (adenosylcobalamin) is found in the mitochondria (the cell's energy factories).

Adenosylcobalamin is produced from methylcobalamin or hydroxycobalamin inside the cell. It serves as a coenzyme for an enzyme involved in a chemical reaction called molecular rearrangement.

  • Increased blood levels of methylmalonic acid can be observed because this enzyme has an inadequate supply of adenosylcobalamin.
  • Without adenosylcobalamin, the body produces long-chain fats containing an odd number of carbons.
  • Robbed of its normal membrane building blocks (long-chain fats with an even number of carbons) produces the characteristic damage to the lipid-rich nervous system that is a hallmark of Vitamin B-12 deficiency.

Premium Brain Support™ contains specialized ingredients because they don't need to be metabolized by the liver, like the synthetic forms found in the typical one-a-day vitamin products.

Methylcobalamin and 5-methyltetrahydrofolate are easily absorbed. This is an enormous advantage for people who have digestive problems. Digestive problems are commonplace and can prevent your body from absorbing vitamins from food.

If you drink any alcohol, take certain medications, or have an infection, you may not be able to absorb or metabolize synthetic vitamins or the building blocks of vitamins found in food.

MEND Solutions™ Premium Brain Support™ doesn't contain Vitamin B-6 because most women take TOO much pyridoxine.

Many women take too much Vitamin B-6 in its non-coenzyme form, pyridoxine. Their average daily intake is 120 mg. Above 200 mg. a day people run a high risk of developing liver and peripheral nerve damage. These problems can slowly develop even at 120 mg a day, especially in smaller individuals who are getting more Vitamin B-6 per pound than larger individuals.

Liver health also varies among people. Hepatitis and other liver diseases, or taking certain medications may cause problems metabolizing Vitamin B-6. Women taking oral contraceptives need supplemental Vitamin B-6.*

*These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure or prevent any disease. All references made for the use of our products are intended for nutritional support to improve normal physiological states and conditions. Any impression made that our products are to be used to treat a disease state or condition should be considered inadvertent and coincidental. Our products are intended to supplement balanced diets.

MEND Solutions™ Premium Brain Support™ ($56.78)


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Fava, M., et al., Folate, B12, and homocysteine in major depression." Am. J. Psychiatry, 154: 426-428, 1997.

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Institute of Medicine, Dietary reference intakes for thiamin, riboflavin, niacin, Vitamin B6, folate, Vitamin B12, pantothenic acid, biotin, and choline. Washington, D.C.: National Academy Press, 1998.

Klee, G.G., Cobalamin and folate evaluation: measurement of methylmalonic acid and homocysteine vs vitamin B-12 and folate. Clin. Chem., 46:1277-1283, 2000.

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Ohta, T., et al., Treatment of persistent sleep-wake schedule disorder in adolescents with methylcobalamin." Sleep, 14: 414-418, 1991.

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Ravaglia, G., et al., Homocysteine and cognitive function in healthy elderly community dwellers in Italy. Am. J. Clin. Nutr., 77: 668-673, 2003.

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Rogers, L.M., et al., Predictors of cobalamin deficiency in Guatemalan school children: diet, Heliocobacter pylori, or bacterial overgrowth? J. Pediatr. Gastroenterol. Nutr., 36: 27-36, 2003.

Rogers, L.M., et al., High prevalence of cobalamin deficiency in Guatemalan schoolchildren: association with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations. Am. J. Clin. Nutr., 77(2): 433-440, 2003.

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